Speaker
Mrs
Maryna Kuzmenko
(Frank Laboratory of Neutron Physics Joint Institute for Nuclear Research)
Description
Fullerenes due to pleiotropic activity are promising agent for different medical applications. They are used as a separate active component and as a carrier of modifications in targeted delivery and/or prolonged therapy.
The fullerenes water solutions, which were prepared by extraction from C60/NMP, characterized by unique small cluster sizes of fullerenes that lead to improved biocompatibility of fullerenes. Based on the aqueous dispersions of fullerene, it was designed a number of drug delivery system as fullerenes-polyphenols, fullerenes-alkaloids, polysaccharides-fullerenes. These systems were investigated by small-angle neutron scattering, dynamic light scattering, and UV-Vis spectroscopy. In addition, a computer model of carrier-drug interaction was proposed based on quantum chemical calculations.
Primary author
Mrs
Maryna Kuzmenko
(Frank Laboratory of Neutron Physics Joint Institute for Nuclear Research)
Co-authors
Dr
Olena Kyzyma
(Kyiv National Taras Shevchenko University)
Timur Tropin
(Joint Institute for Nuclear Research)
