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https://jinr.webex.com/jinr/j.php?MTID=m23f10d08e276f37848aa98c276790793
A stable complex of radionuclide with suitable chelator is one of the key components in design of the radiopharmaceuticals for nuclear medicine. In certain cases the radioactive daughter might be fully or partially released from the complex due to so-called ‘after-effects’, which create the challenges in application of such radiopharmaceuticals [1]. The after-effects strongly depend on the...
Increasing the radiosensitivity of normal and tumor cells is one of the priority aims of modern radiobiology. The agents that modify the yield of DNA double-strand breaks (DSBs) which are lethal to cells are of particular interest. We have previously shown that under the influence of DNA repair inhibitors - 1-β-D-arabinofuranosyl cytosine (AraC) and hydroxyurea (HU) the DNA DSBs yield on cells...
To assess the accumulation of rare earth elements, Hf, Zr, Th, and U in moss species the active moss biomonitoring technique was applied in the Donetsk region. Moss bags with the Ceratodon purpureus and Brachythecium campestre species were exposed for six months in the surroundings of two parks, two steelworks, and a power station. The concentrations of 12 elements (Sc, La, Ce, Nd, Sm, Tb, Yb,...
The search for approaches aimed at changing the sensitivity of cells to the action of ionizing radiation is one of the priority tasks of radiobiology. Studies of the modifying action of agents that affect the processes of DNA damage repair in the cells of the central nervous system (CNS) appear to be promising. In this regard, agents that influence the yield of DNA double-strand breaks (DSB)...
