Mr
Batmunkh Munkhbaatar
(LRB, JINR)
7/4/17, 1:30 PM
A quantitative study of early mechanisms of the central nervous system (CNS) disorders induced by high-energy heavy ions at the molecular and cellular levels is one of urgent problem of modern radiobiology. The present study is focused on the development of optimal models of neuronal morphology for Monte Carlo microdosimetry simulation of initial radiation-induced events of heavy charged...
Mr
Batmunkh Munkhbaatar
(LRB, JINR)
7/4/17, 1:45 PM
Radiation damage to the central nervous system (CNS) has been an on-going challenge for the last decades primarily due to the issues of brain radiotherapy and radiation protection for astronauts during space travel. Although recent findings revealed a number of molecular mechanisms associated with radiation-induced impairments in behaviour and cognition, some uncertainties exist in the initial...
Prof.
Vladimir Lisy
(LRB JINR)
7/4/17, 2:00 PM
Nuclear magnetic resonance (NMR) is non-destructive and one of the best developed tools to study random motion of spins in different systems, including soft tissues such as the brain, heart and muscles. In the long-time limit the current mathematical description of the experiments allows proper interpretation of measurements of normal and anomalous diffusion. The all-time dynamics is correctly...
Mr
Ivan Hornak
(Saarland University)
7/4/17, 2:15 PM
The repositioning of the microtubule organizing center is a part of many fundamental biological processes. It occurs in T-cell lymphocyte immediately after antigen presenting cell is recognized by T-cell. The Dynein's effort to walk to the minus end of the microtubule while being anchored at one place results in microtubule's sliding, and, hence in the repositioning of the microtubule...
Mr
Sergey Poluyan
(Dubna State University)
7/4/17, 2:30 PM
In this study we examine the prospect of using evolutionary optimization algorithms in protein-peptide docking. We present the main assumptions that reduce the docking problem to the continuous global optimization problem and provide a way of using evolutionary optimization algorithms. The Rosetta all-atom force field was used for structural representation and energy scoring. We describe the...
Dr
Nadezhda Fialko
(Institute of Mathematical Problems of Biology RAS – the Branch of Keldysh Institute of Applied Mathematics of Russian Academy of Sciences)
7/4/17, 2:45 PM
Various results of numerous biophysical experiments on charge transfer along DNA fragment have demonstrated that different transport mechanisms are possible in DNA. The transfer rate depends not only on the length of the chain along which the transfer occurs, but also on its sequence [1].
We have studied the simple $1D$-model based on the semi-classical Holstein Hamiltonian for a discrete...
Mr
Stanislav Rykunov
(Institute of Mathematical Problems of Biology RAS - the Branch of Keldysh Institute of Applied Mathematics of Russian Academy of Sciences)
7/4/17, 3:30 PM
The new method to study human brain activity was developed [1]. This method aims to determine spectral characteristics, specific to various regions and structures of the human brain. Said method combines two completely different sources of information: 1) anatomical information, obtained from magnetic resonance imaging(MRI); 2) information about human brain activity, obtained by multichannel...
Mrs
Ekaterina Oplachko
(Keldysh Institute of Applied Mathematics)
7/4/17, 3:45 PM
There is a cloud based resource MathBrain which provides users with tools for time series analysis. The most of methods is dedicated to magnetic- and electro encephalography (MEG, EEG) analysis which originally contains big amount of data to calculate. These methods of brain analysis are noninvasive, and the process looks like a registration of electro-magnetic activity. During the procedure,...
Dr
Tatiana Plyusnina
(Lomonosov Moscow State University)
7/4/17, 4:00 PM
Photosystem II (PSII) is one of the cue protein complexes involved in photosynthesis. It carries out the transfer of electrons from oxygen evolving complex (OEC) to the plastoquinone in the time range from picoseconds to hundreds of milliseconds. The fluorescence emitted by the antenna pigments of PSII is an important marker of the photosynthesis activity. Different phases of fluorescence...
Mr
Sergei Khruschev
(Lomonosov Moscow State University)
7/4/17, 4:15 PM
Protein-protein interactions are of central importance for virtually every process in living matter. Simulation of protein association dynamics is crucial for understanding their functionality. In Brownian dynamics proteins are considered as rigid bodies subjected to electrostatic and random Brownian forces. This rough approximation is rather accurate when protein surfaces do not touch each...
Dr
Tibor Kozar
(Institute of Physics, Pavol Jozef Safarik University, Kosice, Slovakia and Institute of Experimental Physics, Slovak Academy of Sciences, Kosice, Slovakia)
7/4/17, 4:30 PM
The key impact of nanotechnologies on many areas of research and development has become prominent in recent years. Biomedicine belongs to the most influenced fields by nanotechnology, for example thanks to the introduction of theranostics (systems for combined diagnostics and therapeutic utilization). These systems can be composed from metallic core nanoparticles functionalized with...
